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IgG Subclasses in Rhesus‐D Immunization. Effects of Weekly Small Volume Plasmapheresis 1
Author(s) -
VeerKorthof E. T.,
Niterink J.S.G.,
Nieuwkoop J.A.,
Eernisse J.G.
Publication year - 1981
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1981.tb01037.x
Subject(s) - subclass , plasmapheresis , medicine , immunization , antibody , immunology , plasma volume
The IgG subclass composition was determined of the anti‐D antibodies present in the serum of 22 women who had a history of severe rhesus‐D immunization and who weekly underwent small volume plasmapheresis during their current pregnancy. There was no correlation between the subclass patterns of IgG anti‐D antibodies and the degree of illness of the child; the good clinical results obtained with the small volume plasmapheresis could not be explained by a consistent change in the anti‐D IgG subclass composition.