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Red Blood Cell Antibody Screening with Groupamatic System
Author(s) -
Confida S.,
Hurel C.,
Chesnel N.,
Garretta M.,
Muller A.
Publication year - 1981
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1981.tb00666.x
Subject(s) - antibody , red blood cell , medical screening , medicine , red cell , chromatography , immunology , chemistry , gynecology
. The trypsin‐polybren‐citrate (TPC) technique is based on Lalezari's method and has been developed on the Groupamatic equipment to allow the screening of irregular alloantibodies which are not detectable on this machine by the present routine techniques. TPC screening has two main advantages: it gives more reliable results for Rh, Kell, Lewis and P antibodies than bromelin‐methyl‐cellulose, and it permits the screening of Duffy and Kidd antibodies. However, although the TPC technique contributes to an improved quality of the automated screening of blood donor samples, it should not be used as the only method when recipient samples are concerned.