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T k Polyagglutination Produced in vifro by an Endo‐Beta‐Galactoddase 1
Author(s) -
Doînel C.,
Andreu G.,
Cartron J. P.,
Salmon C.,
Fukuda M. N.
Publication year - 1980
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1980.tb02336.x
Subject(s) - bacteroides fragilis , beta (programming language) , escherichia coli , microbiology and biotechnology , antigen , chemistry , biology , biochemistry , immunology , antibiotics , gene , computer science , programming language
. After treatment with the culture supernatant of Bacteroides fragilis or with an endo‐β‐galactosidase from Escherichia freundii , the human red blood cells are T k ‐activated, i.e. agglutinable by BS II lectin and their blood group I and i activities are reduced. These results suggest that B. fragilis produces an endo‐β‐galactosidase activity and that the main antigenic determinant of T k polyagglutinable red cells is a terminal N‐acetyl‐glucosamine residue.