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Some Notes on the Specificity of Anti‐A 1 Reagents
Author(s) -
Lopez M.,
Benali J.,
Cartron J.P.,
Salmon C.
Publication year - 1980
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1980.tb01870.x
Subject(s) - saliva , reagent , antigen , blood group antigens , microbiology and biotechnology , phenotype , red blood cell , chemistry , immunology , medicine , biology , biochemistry , organic chemistry , gene
. The agglutinability of red blood cells of A 1 , A 2 , A 3 , A x and cis‐AB phenotypes by several anti‐A 1 reagents was quantitatively evaluated and found to correlate with the number of A antigenic sites/cell determined by using 125 I‐labelled IgG anti‐A. Moreover, anti‐A 1 sera could be absorbed by some A 2 red blood cells and were inhibited by concentrated saliva from A 2 secretor individuals. The significance of these findings is discussed in the light of recent data from the literature.