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Efficacy of 100 μg (250IU 1 ) Anti‐D IgG in the Prevention of Rh‐Haemolytic Disease
Author(s) -
Simonovits I.,
Böröcz Irene
Publication year - 1979
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1979.tb04393.x
Subject(s) - medicine , haemolytic disease , abo blood group system , immunization , serology , significant difference , rh blood group system , gastroenterology , immunology , pediatrics , antibody , obstetrics , pregnancy , fetus , genetics , biology
. In the years 1975–1976, 6, 766 unselected (ABO compatible and incompatible) primigravidae parturients with uncomplicated delivery were given 100 μg (250 IU) anti‐D IgG. A total of 4,473 presented for the 6‐month control examination. IAGT was positive in 5 cases (0.11%). The 200 μg (500 IU) dose was administered to 1,543 women. Of these, 962 presented for serological control. IAGT was positive in 1 case (0.10%). The difference is not significant. The findings support the results of previous studies suggesting that 100 μg anti‐D is a sufficient dose to prevent immunization in uncomplicated deliveries.