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Activity of IgG and IgM ABO Antibodies against Some Weak A (A 3 , A x , A end ) and Weak B (B 3 , B x ) Red Cells
Author(s) -
Lopez M.,
Benali J.,
Bony V.,
Salmon Ch.
Publication year - 1979
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1979.tb02305.x
Subject(s) - antibody , abo blood group system , immunoglobulin m , immunology , immunoglobulin g , b cell , microbiology and biotechnology , biology , chemistry
. The IgG and IgM anti‐A and anti‐B activities from several immune and non‐immune O, A and B sera were tested against a panel of weak A (A 3 , A x , and A end ) and weak B (B 3 and B x ) red cells. In all cases it is the IgM which agglutinated optimally A x (or B x ) cells, while IgG and IgM anti‐A (or anti‐B) reacted similarly with A 3 and A en d (or B 3 ) cells. The agglutinating activity of all these ABO antibodies was found straightly related to their association constant for the A (or the B) receptor.