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Expression of T‐Antigen on Polyagglutinable Erythrocytes and Carcinoma Cells: Preparation of T‐Activated Erythrocytes, Anti‐T Lectin, Anti‐T Absorbed Human Serum and Purified Anti‐T Antibody
Author(s) -
Howard Donald R.
Publication year - 1979
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1979.tb02279.x
Subject(s) - antibody , antigen , lectin , microbiology and biotechnology , chemistry , immunology , rh blood group system , biology
. Recent interest has been revived in the human MN blood group system due to the discovery of the MN precursor substance (T‐antigen) on certain malignant, but not benign or normal tissues. Methods for preparing T‐activated erythrocytes, anti‐T lectin, anti‐T absorbed human serum and purified anti‐T antibody are described and should be useful not only to the researcher involved in this new line of investigation, but also to the routine blood bank faced with the occasional problem of erythrocyte polyagglitinability.