Premium
Ethanol and Heath‐Treated Plasma Fractionation Methods in South Africa
Author(s) -
Villiers V.,
Wilson J. G. S.
Publication year - 1978
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1978.tb02956.x
Subject(s) - fractionation , albumin , ethanol , chromatography , chemistry , globulin , human albumin , biochemistry , medicine , immunology
. Modifications of the Cohn techniques are the methods of choice for the preparation of dilute albumin (PPS) and γ‐globulin solutions on an industrial scale. For the manufacture of refined albumin solutions, however, considerable labour and material is saved if crude, ethanol‐precipitated fractions are heated in the presence of stabilisers in order to purify the albumin. The technique is simple and cheap, and yields a safe product of high quality. Bacterially contaminated and highly haemoglobinized plasma can be successfully heat‐treated.