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Redistribution of Platelets During Discontinous Flow Platelet Pheresis
Author(s) -
Katz Alfred J.,
Reiss Robert F.,
Houx Judith A.
Publication year - 1978
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1978.tb02944.x
Subject(s) - platelet , spleen , chemistry , plateletpheresis , redistribution (election) , immunology , medicine , apheresis , politics , political science , law
Abstract. Greater numbers of platelets are recovered during discontinuous flow centri‐fugation than can be simply accounted for by the decrease in total circulating platelets in the donor. There is a linear relationship between the logarithm of the circulating platelet count and the number of plateletpheresis bowls filled. The disappearance of platelets from the peripheral circulation occurs at a greater rate in splenectomized donors than in normal donors, and the rate of platelet disappearance in normal donors is less than what would be expected if there were no in vivo platelet storage pools. The data suggest the redistribution of platelets from the spleen in normal donors during the time course of the procedure.