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New Hepatitis B Surface Antigen Subtypes inside the ad Category
Author(s) -
CouroucéPauty A. M.,
Lemaire J. M.,
Roux J. F.
Publication year - 1978
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1978.tb02939.x
Subject(s) - virology , epidemiology , hepatitis virus , medicine , virus , demography , pathology , sociology
. In addition to the 10 HBs Ag subtypes already described, 2 new subtypes were defined by using the q determinant. Exceptions to the rule generally accepted were found in that the q determinant was only lacking in HBs Ag/adw 4 . These exceptions occurred in adw and adr categories. These 2 new subtypes are adw q positive and adr q negative. Out of 98 HBs Ag/adw 4 from silent carriers and patients from different parts of the world, mainly from France (79), 6 were found q positive. 3 out of these 6 cases came from Montpellier (South of France) and another 3 from Germany. The 92 other cases were found q negative. Further studies will be necessary to better know the location of this new subtype adw 4 q positive, but it seems to be present only in certain parts of Europe. Out of 86 HBs Ag/ adr from silent carriers from Asia (58), Oceania (17), France (10, most of them contaminated in Asia) and Reunion (1), 10 were found q negative. All these 10 cases were detected in Oceania, 2 out of 2 in carriers from New Caledonia and 8 out of 13 from French Polynesia. The new subtype adr q negative seems localized in Melanesia and Polynesia and absent from Asia. These 2 new markers of hepatitis B virus will allow better epidemiological and geographical studies.