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Conceptual Framework Shifts in Immunogenetics
Author(s) -
Hirschfeld Jan
Publication year - 1978
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1978.tb02905.x
Subject(s) - typing , simple (philosophy) , immunogenetics , set (abstract data type) , inclusion (mineral) , population , conceptual framework , computer science , computational biology , combinatorics , mathematics , chemistry , biology , genetics , epistemology , sociology , philosophy , antigen , demography , mineralogy , programming language
. Two Caucasian population materials totalling 530 individuals and 3,180 typing results are analyzed with regard to various combinations of the Ag(x, y, a 1 , d, c, g) factors. Superficially, both materials appear well aligned to each other and the contemporary (simple‐complex) framework. However, when the same set of data are structuralized within a new (complex‐simple) framework, the typing results for 12 of 362 or 3.3% of the Swiss and no less than 19 of 168 or 11.3% of the English samples are not compatible with the new framework specifying that the various anti‐Ag reagents can be arranged in two ‘inclusion groups’ ‐ the anti‐Ag (y > d > c) and the anti‐Ag (g > ax > x) series.