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Anti‐Fab‘ Antibodies in Human Sera
Author(s) -
Vos G. H.
Publication year - 1977
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1977.tb02231.x
Subject(s) - antibody , medicine , incidence (geometry) , pregnancy , immunology , isoantibodies , biology , physics , optics , genetics
. Antibodies to the Fab' fragments of human IgG are commonly found in human sera. This study shows that the incidence of such antibodies is higher in women, both blood donors and hospital patients, than in men: it is no higher in patients with malignant disease than in hospital patients of the same sex without malignancies. The incidende in hospital patients is always greater than in healthy blood donors. The presence of Fab' antibodies is not related to pregnancy. The greatest difference in the frequency of such antibodies occurs between males and females under the age of 50.