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A Further Example of Kp a /K o Exhibiting Depression of some Kell Group Antigens
Author(s) -
Ford D. S.,
Knight A. E.,
Smith F.
Publication year - 1977
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1977.tb00633.x
Subject(s) - antigen , blood group antigens , microbiology and biotechnology , group (periodic table) , depression (economics) , chemistry , medicine , immunology , biology , organic chemistry , macroeconomics , economics
. This paper gives details of a family in which there are numerous examples of the heterozygous K o state. The Study was initiated by the presence of anti‐Kp b in the serum of the propositus. Reactions with anti‐k, anti‐Ku, anti‐Js b and anti‐K13 confirm that the K o gene in trans with Kp a results in weaker expression of these Kell antigens. One example of anti‐k showed some evidence of dosage effect with kKp b /K° cells, but these results were not confirmed by quantitation studies.