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False‐Positive Rose‐Waaler Rheumatoid Factor Titre Given by Anti‐Ruminant IgM Antibody
Author(s) -
Johnson P. M.,
Reading C. A.,
Holborow E. J.,
Holdstock D. J.
Publication year - 1976
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1976.tb04461.x
Subject(s) - titer , antibody , rheumatoid factor , immunology , medicine , biology
. An antibody against ruminant (goat, sheep, bovine) IgM is described which also cross‐reacts with rabbit IgM. The antibody was found in the serum of a patient with adult coeliac disease and a selective IgA deficiency. This patient gave a false high Rose‐Waaler rheumatoid factor titre due to the presence of the serum antibody to rabbit IgM that was capable of agglutinating rabbit antibody‐sensitised erythrocytes.