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Albumin Autoagglutinating Phenomenon as a Factor Contributing to False Positive Reactions when Typing with Rapid Slide‐Test Reagents
Author(s) -
Case J.
Publication year - 1976
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1976.tb02849.x
Subject(s) - reagent , typing , bovine serum albumin , blood typing , albumin , chromatography , latex fixation test , chemistry , medicine , immunology , biology , microbiology and biotechnology , biochemistry , antibody , organic chemistry
. A case of albumin autoagglutination has illustrated the point that this phenomenon may be a further source of false positive reactions when typing with rapid slide‐test reagents. As agglutination only occurred with the bovine albumin solution and slide‐test reagents from a single manufacturer, it is evident that control tests must be performed not merely with a high protein solution duplicating the formulation of the slide‐test reagent itself, but with one from the same commercial source as the reagent.