Premium
A Second Example of Anti‐Fy5 1
Author(s) -
DiNapoli Janet,
Garcia Alicia,
Marsh W. L.,
Dreizin D.
Publication year - 1976
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1976.tb02833.x
Subject(s) - antibody , microbiology and biotechnology , antigen , phenotype , chemistry , rh blood group system , regulator , gene , biology , immunology , biochemistry
. Anti‐Fy5 has been found in the serum of a transfused Fy(a–b–) Negro woman. The antibody reacts with red cells that are Fy(a+) or Fy(b+) or both, but not with Fy(a–b–) cells or with cells of the Rh null phenotype. Rh null red cells of both amorph and regulator types are nonreactive with anti‐Fy5. If interaction between Rhesus and Duffy gene products is necessary for Fy5 antigen synthesis, it must be the Rh gene itself and not the X 1 r modifier that is involved.