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Immunological Properties of a Human Macroglobulin Bearing Antigenic Determinants of μ‐ and γ‐Chains
Author(s) -
Aguilera Sergio,
Moreno Carlos
Publication year - 1976
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1976.tb02824.x
Subject(s) - pepsin , macroglobulin , cryoglobulin , antigen , chemistry , dissociation (chemistry) , immune system , immunology , biochemistry , biology , enzyme , cryoglobulinemia , virus , organic chemistry , hepatitis c virus
. The immunochemical properties of a human IgM cryoglobulin bearing determinants belonging to human IgG are presented. Dissociation of possible immune complexes, separation of H and L chains, and pepsin digestion were performed and the effect on the cross‐reactivity assessed.