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Quantitative Immunological Study of Pregnancy‐Associated α 2 ‐Globulin Antigen
Author(s) -
Than G. N.,
Csaba I. F.,
Szabó D. G.,
Karg N. J.,
Novák P. F.
Publication year - 1976
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1976.tb02803.x
Subject(s) - pregnancy , gestation , globulin , medicine , placenta , antigen , blood proteins , obstetrics , fetus , endocrinology , immunology , biology , genetics
. Pregnancy‐associated α 2 ‐globulin antigen, a protein which is practically absent from the serum of nonpregnant individuals or could be found in the quantity of only a few milligram percent, gradually accumulates during pregnancy. A peak value of 86 ± 44 mg% is reached by the 31st week of gestation. In the last 2 months of pregnancy a decrease was observed to 65 ± 30 mg% before delivery. Significantly lower levels of this protein could be found in prolonged pregnancy and in cases of abortions associated with placental destruction. Elevated amounts of this characteristical pregnancy protein could be found in 63% of 100 tumor patients.