Premium
Gas Chromatographic Trace Analysis of β‐Propiolactone in Sterilized Serum Proteins
Author(s) -
Pruggmayer D.,
Stephan W.
Publication year - 1976
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1976.tb02209.x
Subject(s) - chromatography , chemistry , hydrolysis , residual , recovery rate , biochemistry , mathematics , algorithm
. A method for detecting traces of β‐propiolactone, which was previously described by S chmitz ‐M asse , has been modified and adapted to the analysis of protein solutions. Using this method, the rate of hydrolysis of β‐propiolactone (β‐P1) was examined and β‐P1 sterilized commercial products were analyzed for possible residual nonhydrolyzed β‐P1.