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Detection of Hepatitis B Antigen m Blood Donors by Radioimmunoassay and Three Reverse Passive Haemagglutination Techniques
Author(s) -
Seidl S.,
Ziegler G. B.
Publication year - 1976
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1976.tb02192.x
Subject(s) - radioimmunoassay , hemagglutination , antigen , hepatitis b , medicine , virology , immunology
. In a comparative study 5,569 sera from voluntary donors were tested simultaneously for hepatitis B antigen by three reverse passive haemagglutination (RPHA) techniques (Auscell®, Hepanosticon®, Hepatest®) and the radioimmunoassay (RIA) (Ausria II). Among the three RPHA methods, no significant differences could be found as far as sensitivity is concerned. The percentage of positive sera detected by these RPHA methods varies from 0.43 to 0.56%. Eleven sera were detectable only by Ausria II. Except for two, all these sera had low counts per minute in the RIA.