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Effect of Modification of Amino Groups of Human Erythrocytes on M, N and N Vg Blood Group Specificities
Author(s) -
Lisowska Elwira,
Duk Maria
Publication year - 1975
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1975.tb02786.x
Subject(s) - agglutinin , acetic anhydride , biochemistry , chemistry , microbiology and biotechnology , lectin , biology , catalysis
. Modification of amino groups on the surface of human erythrocytes by acetic anhydride and trinitrobenzenesulfonic acid caused loss of agglutinability by human and rabbit anti‐M and anti‐N sera, was without any effect on agglutinability of N red cells by Vicia graminea agglutinin, and made M cells agglutinable by the same agglutinin. Modification of amino groups had no effect on agglutinability of red cells by anti‐H and anti‐A lectins and only slightly decreased agglutinability by human anti‐H, anti‐A and anti‐I sera. The results suggest that the difference between M and N receptors is not determined by the structure of oligosaccharide chains.