Premium
Histocompatibility Antigens in Leprosy 1
Author(s) -
Smith George S.,
Walford Roy L.,
Shepard Charles C.,
Payne Rose,
Prochazka George J.
Publication year - 1975
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1975.tb02739.x
Subject(s) - leprosy , histocompatibility , antigen , lepromatous leprosy , typing , medicine , population , immunology , biology , human leukocyte antigen , genetics , environmental health
. Results of HL‐A typing are presented in 82 patients with leprosy and 50 normal Filipinos from Cebu, and 144 normal Filipino immigrants from the Luzon area. Comparisons of HL‐A antigen frequencies among the total patients and normals of Cebu showed no statistically significant differences; however, HL‐A10 was increased in frequency among the patients with lepromatous disease compared to the normals, and HL‐A5 was increased among the tuberculoid patients compared to the lepromatous patients. None of these comparisons was statistically significant when corrected for the number of antigens tested. Comparisons of HL‐A antigen frequencies between normal Filipinos of the Cebu and Luzon regions showed increased W‐5 in the Luzon population (corrected p < 0.025).