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Complement Fixing and Lymphocytotoxic Antibodies in Serum of Pregnant Women at Delivery
Author(s) -
Nymand Gunnar
Publication year - 1975
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1975.tb02738.x
Subject(s) - complement (music) , antibody , medicine , pregnancy , immunology , isoantibodies , obstetrics , biology , phenotype , genetics , complementation , gene
. The paper concerns 275 sera of pregnant women at delivery containing complement fixing platelet antibodies (CFPAb) and/or lymphocytotoxic antibodies (LCTAb). 79 sera contained operationally monospecific antibodies against platelets and/or lymphocytes. 10 sera had only CFPAb, 4 of these were C‐fix anti‐A. 41 sera had CFPAb and LCTAb, 18 of these were monospecific against platelets and/or lymphocytes. In 224 sera only LCTAb could be demonstrated, 57 were monospecific. Furthermore in 8 of 258 primigravidae, screened for LCTAb 6 months post partum , antibodies were detected. Generally the antibodies present at delivery had disappeared or narrowed, but in 3 cases the antibodies were detectable only in the postpartum sample.