Premium
Development of Direct Antiglobulin Reaction Accompanying Alloimmunization in a Patient with Rh d (D, Category III) Phenotype 1
Author(s) -
Lalezari Parviz,
Talleyrand Nancy P.,
Wenz Barry,
Schoenfeld Martha E.,
Tippett Patricia
Publication year - 1975
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1975.tb02736.x
Subject(s) - autoantibody , phenotype , titer , rh blood group system , antibody , medicine , immunology , isoantibodies , hemagglutination tests , chemistry , hemagglutination , biochemistry , gene
. New examples of the Rh d (D, category III) red cell phenotype are described in three siblings. One of these individuals who had previously been transfused, received three units of Rh o (D) positive blood several years later and developed a high titer anti‐Rh D antibody. This anamnestic response was associated with the development of an autoantibody which persisted for a period of at least 8 months. This observation represents another example of autoimmunization which has rarely been observed to accompany alloimmunization.