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Separation of ABH, I, Ss Antigenic Activity from the MN‐Active Sialoglycoprotein of the Human Erythrocyte Membrane
Author(s) -
Anstee D. J.,
Tanner M. J. A.
Publication year - 1975
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1975.tb00522.x
Subject(s) - sialoglycoprotein , abo blood group system , antigen , glycoprotein , erythrocyte membrane , serology , biology , sialoglycoproteins , chemistry , glycolipid , membrane glycoproteins , microbiology and biotechnology , rh blood group system , biochemistry , immunology , membrane , antibody
. The erythrocyte sialoglycoprotein was purified from cells with complementary ABO(H), MN and Ss phenotypes. Serological examination of the sialoglycoprotein preparations demonstrated that this molecule does not carry the ABO(H), I or Ss antigens. The results also suggest that Ss activity may be associated with a minor erythrocyte glycoprotein. The characteristics of the ABO(H) and I antigens are consistent with earlier suggestions that these antigens are carried on complex glycolipids.