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A New Reversed Passive Hemagglutination Test for Detection of HBsAg
Author(s) -
Prince Alfred M.,
Ikram Hafeez,
Chicot Doris,
Wright Rebecca,
Vnek John,
Neurath Robert,
Lippin Arnold,
Swiss Stephen
Publication year - 1975
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1975.tb00516.x
Subject(s) - hbsag , hemagglutination , radioimmunoassay , virology , hemagglutination tests , volunteer , hemagglutination assay , medicine , antibody , hepatitis b , immunology , biology , hepatitis b virus , virus , titer , agronomy
. A new reversed passive hemagglutination test for HBsAg, termed Raphadex B, has been developed using immunochemically purified chimpanzee anti‐HBs bound to stabilized human erythrocytes. The test has been found to have equivalent sensitivity to the Ausria 125 I radioimmunoassay, and detected a similar number of HBsAg‐containing specimens in screening of volunteer blood donors. This method offers an economical approach to third generation methodology for hepatitis B screening of blood donors.