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A Sensitive Test for Antibody Against the Hepatitis B Core Antigen (Anti‐HB c ) 1
Author(s) -
Greenman R. L.,
Robinson W. S.,
Was G. N.
Publication year - 1975
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1975.tb00481.x
Subject(s) - antibody , virology , antigen , hepatitis b , medicine , hepatitis b virus , microbiology and biotechnology , hepatitis c virus , immunology , virus , biology
. Radioimmunoprecipitation of Dane particle core radiolabeled in a DNA polymerase reaction was used for detecting anti‐HB c in the sera of blood donors positive for HB B Ag and patients with acute hepatitis B. The test for anti‐HB c was a specific and sensitive indicator of current or recent virus infection. Human anti‐HB S hyperimmune immunoglobulin contained small amount of anti‐HB c , but the antibody was not detected in the serum of hyperimmunized chimpanzees.