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The Action of Group Bm or CisAB Sera on Group O Red Cells in the Presence of UDP‐D‐Galactose
Author(s) -
Kogure Tadahisa
Publication year - 1975
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1975.tb00476.x
Subject(s) - titer , group a , group b , galactose , galactosyltransferase , agglutination (biology) , chemistry , red cell , microbiology and biotechnology , antibody , biochemistry , biology , immunology , medicine , enzyme
. Group B and AB sera, acting on O red cells in the presence of UDP‐galactose, each converted them into B active cells, which were agglutinated by anti‐B human serum (1:512) at the titer of 128‐fold, while group Bm and A 1 Bm sera, converted O red cells similarly incubated into B active cells, which were agglutinated by anti‐B human serum (1:512) at the titer of 8‐ to 16‐fold. This indicates that α‐galactosyltransferase activity in B m and A 1 Bm sera may be about ⅛‐⅙ that in B and AB sera. Group CisAB sera, even after absorption of cold anti‐B agglutinins with packed, washed group B red cells, did not convert O red cells in the presence of UDP‐galactose in such a way that they might agglutinate against anti‐B human serum.