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Serology and Genetics of the A 1 High H Subgroup
Author(s) -
Sathe Malti,
Bhatia H. M.
Publication year - 1974
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1974.tb02708.x
Subject(s) - serology , dolichos , incidence (geometry) , genetics , antigen , inheritance (genetic algorithm) , biology , demography , medicine , gene , mathematics , botany , antibody , geometry , sociology
. Tests on 1,000 A group Indians in Bombay showed high H content in 5%. This incidence was the same in Maharashtrians and Gujarathis. A 1 subjects with high H had a mean score for A 1 antigen of 22.54 ( Dolichos ) which was slightly more than or equivalent to A 1 individuals (19.66). Ulex gave a score of 9.7 in comparison to 0.55 for A 1 and 16.5 for A 2 . Absorption studies confirmed higher A and H antigen expression than in A 2 and A 1 individuals, respectively. Family studies of eight A 1 /high H individuals showed no specific inheritance pattern. Various hypotheses to explain the irregular inheritance pattern have been discussed.