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Absence of B Antibody in a Blood Group A 1 Person 1
Author(s) -
Springer G. F.,
Tegtmeyer Herta
Publication year - 1974
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1974.tb02693.x
Subject(s) - saliva , antibody , group a , group b , serology , immunology , abo blood group system , hemolysis , hemolysin , red blood cell , immunization , biology , medicine , biochemistry , virulence , gene
. A healthy Caucasian woman who possessed blood groups A 2 H(O) on her red cells as well as in her saliva and serum had no anti‐blood group B ‘complete’ or ‘incomplete’ agglutinins nor hemolysins as determined either on whole serum or its concentrated β‐γ‐globulin fraction. No anti‐B antibody was stimulated by immunization with highly active human blood group B glycoprotein. No blood group B antigenic determinants were demonstrable on the proposita's red cells or in her saliva by any of numerous serological and enzymatic methods at various red cell concentrations between 2 and 37 °C, nor by the highly sensitive immunoglobulin‐latex test. Immunization with the proposita's red cells did not elicit anti‐blood group B antibodies in chickens or rabbits. Blood groups A and O but not B occurred in members of this woman's family which was studied through 3 generations.