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A New Rare Blood Group Antigen, ‘FAR’, Probably Linked to the MNSs System
Author(s) -
Cregut R.,
Liberge G.,
Yvart J.,
Brocteur J.,
Salmon C.
Publication year - 1974
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1974.tb02687.x
Subject(s) - antigen , antibody , immunology , biology , immune system , locus (genetics) , isoantibodies , medicine , genetics , gene
. A new, rare antigen, FAR, was discovered in connection with a hemolytic disease of the newborn. This very rare antigen was not encountered in 14,273 Caucasians tested. It is probably linked to the MNSs system (p < 0.004). The anti‐FAR antibody, which is of immune origin, is also very rare: it has been sought unsuccessfully in 541 sera. The identification of this antigen provides further evidence of a comparatively high mutation rate in some sites on the MNSs locus and of its practical interest in both pathology and human genetic studies.