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Gm (Ray), a New Allotypic Marker on Human IgG 3 1
Author(s) -
Schanfield M. S.,
Fudenberg H. H.
Publication year - 1974
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1974.tb02678.x
Subject(s) - antigen , inheritance (genetic algorithm) , biology , antibody , microbiology and biotechnology , immunology , genetics , gene
. A new antigenic determinant on the majority of human IgG 3 is described. The new antigen is found in the sera of all Gm(g)‐positive individuals and the majority of Gm(b)‐positive individuals. Only those individuals homozygous for Gm(c 5 ) are negative for the new antigen. Family studies verify the inheritance and indicate that the new antigen behaves as an alternate substitution to Gm(c 5 ) in man.