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Association between HL‐A and Red Cell Antigens. An AutoAnalyzer Study
Author(s) -
Nordhagen R.,
Ørjasæter H.
Publication year - 1974
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1974.tb02674.x
Subject(s) - autoanalyzer , cytotoxic t cell , antibody , antigen , immunology , chemistry , histocompatibility , microbiology and biotechnology , human leukocyte antigen , medicine , biology , biochemistry , in vitro , chromatography
. Sera containing cytotoxic HL‐A antibodies were examined in order to detect red cell antibodies, using an AutoAnalyzer. In sera with cytotoxic anti‐HL‐A2 antibodies, we were able to demonstrate haemagglutinins that reacted mainly with red cells from HL‐A28 positive donors. In sera with cytotoxic anti‐HL‐A8 antibodies, we found antibodies that reacted with red cells from some, although not all, HL‐A8 positive donors. The haemagglutinins gave indentical and highly reproducible reaction patterns, but there were marked variations in antigenic strength.