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Reactivity of Monkey Erythrocytes in Immune Adherence
Author(s) -
Schwartz Jeanna,
Vardi Nurith
Publication year - 1974
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1974.tb02672.x
Subject(s) - immune adherence , primate , agglutination (biology) , antibody , immune system , biology , immunology , negativity effect , antigen , red blood cell , virology , hemagglutination , psychology , ecology , social psychology
. Blood samples from 31 humans and 21 monkeys (9 Cercopithecus aethiopiae, 7 Macacus rhesus and 5 Papio anubis ), were examined for suitability in the immune‐adherence phenomenon, which is known to provoke agglutination of ‘primate’ red cells, when added to an antigen‐antibody complex in presence of complement. The 21 monkey blood samples were all negative; in the meantime, under same conditions, only 5 of 31 human blood samples were unsuitable (similar values were obtained with human blood samples in prior research). The high frequency of negativity among the three monkey genera is probably due to the absence of a surface receptor on their red cells; suitability of primate red cells for immuneadherence should be reconsidered in accordance with this finding.