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Antiglobulin Test in Low‐Ionic Strength Salt Solution for Rapid Antibody Screening and Cross‐Matching
Author(s) -
Löw B.,
Messeter L.
Publication year - 1974
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1974.tb02666.x
Subject(s) - ionic strength , salt (chemistry) , saline , suspension (topology) , salt solution , chromatography , chemistry , antibody , incubation , ionic bonding , medicine , immunology , biochemistry , mathematics , ion , organic chemistry , homotopy , aqueous solution , pure mathematics
. A modification of the conventional antiglobulin test for routine use is described. Saline as the red cell suspension medium is substituted with salt solution of low ionic strength. This permits a considerable decrease in the incubation time, which is of practical importance in clinical work. The sensitivity of the reaction does not seem to be decreased by this procedure, in some instances even an increase in reaction strength can be observed.