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Characterization of a Human Saliva Antigen Precipitated by a Lectin from Lotus tetragonolobus 1
Author(s) -
Napier Pamela W.,
Everhart D. L.,
Grundbacher F. J.
Publication year - 1974
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1974.tb02441.x
Subject(s) - saliva , antigen , abo blood group system , lectin , h antigen , precipitin , microbiology and biotechnology , ouchterlony double immunodiffusion , lotus , chemistry , glycoprotein , biology , biochemistry , immunology , botany , antiserum
. Ouchterlony precipitin tests give visual evidence that extracts from Lotus tetragonolobus contain two different lectins. In addition to the H antigen, Lotus identifies another antigen, called the L antigen, which is not the A, B, Le a , Sd a , I or SC 1 saliva antigen and has been found in variable strength in secretor and nonsecretor saliva of individuals of all ABO blood groups. The L antigen is part of a cathode migrating glycoprotein. Sugar inhibition studies reveal that the terminal sugars are the same as for the H and Le a antigens, the presumable difference being that l ‐fucose is attached to a different site. The L antigen is absent in the saliva and red cells of the Bombay type, but red cells of all other individuals absorb both lectins from Lotus extract.