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The Selection of Plasma for the Preparation of Antitetanus Immunoglobulin
Author(s) -
Entwistle C. C.,
Eldrlnge P. L.
Publication year - 1973
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1973.tb04368.x
Subject(s) - toxoid , antitoxin , tetanus , tetanus antitoxin , medicine , antibody , immunology , vaccination , biology , toxin , microbiology and biotechnology
Abstract. The use of IEOP is described for screening blood donors to find plasma containing tetanus antitoxin suitable for fractionation. Preliminary results indicate that most recipients of tetanus toxoid are unlikely to have acceptable antitoxin levels for much longer than about three months after inoculation. A small number of recipients maintain acceptable levels even for many years without further known boosting. Such people can now be identified easily, among the 5% of all East Anglian donors who have antitoxin levels of at least 5 1U/ml.