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The Action of Seed and Other Reagents on En(a‐) Erythrocytes
Author(s) -
Bird G. W. G.,
Wingham June
Publication year - 1973
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1973.tb03856.x
Subject(s) - agglutinin , reagent , protease , biology , red cell , glycoprotein , biochemistry , chemistry , lectin , enzyme , medicine
. The action of various seed agglutinins and other reagents on red cells of the rare phenotype En(a‐) is described. It is shown that En(a‐) red cells appear to lack part of the protease‐labile glycoprotein portion of the cell membrane. The specificity of some of the seed reagents is discussed. The Maclura aurantiaca receptor on En(a‐) cells is depressed, so that the agglutinins from Maclura seeds react much more weakly with En(a‐) than with En(a +) cells. The Maclura agglutinin may therefore be loosely described as ‘anti‐En a ’.
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