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Alternatives to Freeze‐Drying for the Removal of Ethanol from Plasma Proteins
Author(s) -
Smith J. K.,
Watt J. G.,
Watson C. N.,
Mastenbroek G. G. A.
Publication year - 1972
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1972.tb05119.x
Subject(s) - ethanol , fraction (chemistry) , human albumin , chromatography , albumin , chemistry , freeze drying , blood proteins , biochemistry
. An alternative to freeze‐drying for the removal of ethanol from human albumin (Cohn fraction V) is described. Up to 50 kg fraction V, after solution in water, is heated during a brief passage through an evacuated chamber. Several methods are described permitting optimal rate of water or ethanol removal, or minimal polymerisation of albumin.