Premium
Another Example of Isoimmune Neonatal Neutropenia Due to Anti‐Na1
Author(s) -
Weerdt Ch. M. van der,
Lalezari P.
Publication year - 1972
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1972.tb03991.x
Subject(s) - neutropenia , transplacental , antibody , medicine , immunology , fetus , pregnancy , biology , toxicity , placenta , genetics
. A review of the present knowledge of transplacental transmission of anti‐neutrophil antibodies is given. A family in which one, possibly two of the three children had severe neutropenia after birth with subsequent infections, is described. An agglutinating antibody, directed against the neutrophil‐specific antigen NA 1, was demonstrated in the maternal serum. The father and all three children were NA 1‐positive. This case is another example of isoimmune neonatal neutropenia due to anti‐NA 1 antibodies.