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Clostridial‐Induced Type I Polyagglutinability with Associated Intravascular Hemolysis
Author(s) -
Gray J. M.,
Beck M. L.,
Oberman H. A.
Publication year - 1972
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1972.tb03984.x
Subject(s) - hemolysis , lysis , in vivo , in vitro , ex vivo , microbiology and biotechnology , chemistry , receptor , immunology , biology , biochemistry
Summary A woman with a clostridial septicemia manifested in vivo type I polyagglutinability of her erythrocytes, presumably due to activation of the latent T‐receptor. A filtrate of the Clostridium culture was capable of causing T‐activation of erythrocytes in vitro and bacterial products probably caused the T‐activation in vivo . Moreover, there was evidence that anti‐T in donor plasma caused lysis of T‐active red cells.