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IgG Cold Agglutinins and First Trimester Abortion
Author(s) -
Mygind K.,
Ahrons S.
Publication year - 1972
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1972.tb03849.x
Subject(s) - cold agglutinin , first trimester , antibody , abortion , medicine , immunology , pregnancy , agglutinin , chemistry , biology , fetus , genetics , lectin
. Two patients with first trimester abortion and idiopathic cold agglutinin syndrome due to cold auto‐antibodies of the IgM and IgG immunoglobulin classes are reported. Sucrose gradient ultracentrifugation and 2‐mercapto‐ethanol treatment indicated the presence of IgM as well as IgG cold agglutinins. The possible relationship between the abortions and these cold agglutinins is discussed.