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Anti‐Lu8, an Antibody Recognizing Another Lutheran‐Related Antigen
Author(s) -
MacIlroy Mija,
McCreary Joan,
Stroup Marjory
Publication year - 1972
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1972.tb03835.x
Subject(s) - antibody , antigen , microbiology and biotechnology , biology , immunology , medicine , chemistry
. An antibody defining another high‐frequency antigen within the Lutheran system, designated as anti‐Lu8, has been found in the serum of a Caucasian woman. The serum is compatible with Lu(a‐b‐) cells of the dominant and recessive types but reacts with Lu(a‐b+) cells that are Lu(‐4), Lu(‐5), Lu(‐6) and Lu(‐7). All of the family members are Lu(a‐b+). The red cells of two of the four siblings are not agglutinated by the serum but the red cells of her parents and two children are agglutinated suggesting that Lu8 is controlled by an autosomal dominant gene.