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Hemoglobin G Chinese in Chinese Subjects in Taiwan
Author(s) -
Blackwell R. Q.,
Weng M.I.,
Liu C.S.,
Shih T.B.,
Wang C.L.
Publication year - 1972
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1972.tb03472.x
Subject(s) - hemoglobin , glutamine , hemoglobin s , incidence (geometry) , medicine , chinese people , traditional medicine , gastroenterology , china , genetics , biology , history , mathematics , geometry , disease , amino acid , sickle cell anemia , archaeology
. Hemoglobin G Chinese, obtained from Chinese subjects in Singapore, Honolulu, and Hong Kong, was shown by Swenson, Hill, Lehmann and Jim [J. biol. Chem. 237 : 1517–1520 (1962)] to be an α‐chain variant in which glutamine replaces the glutamyl group normally located at position α‐30. The same variant has now been found in 7 unrelated Chinese subjects on Taiwan. From the present studies, the incidence of Hemoglobin G Chinese in Chinese subjects in Taiwan is estimated to be approximately 5/100,000.