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The Rh System
Author(s) -
Chown B.,
Lewis Marion,
Kaita Hiroko
Publication year - 1971
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1971.tb04794.x
Subject(s) - genetics , gene , mutation , phenotype , biology , rh blood group system , antibody
. A consanguineous ♂R 1 R 2 × ♀R 1 R 1 mating is reported which produced one child, four R 1 R 1 and two R 1 R 2 children. Nonpaternity and nonmaternity are ruled out as an explanation for the anomalous phenotype. The authors produce evidence indicating that this is indistinquishable from heritable and deduce from that it is, therefore, identical with that gene. Three explanations are offered for its occurrence here and two discarded. The third is a mutation: they favor the hypothesis that in this they are seeing the expression of a ‘gene of control’ and its effect on a ‘gene of structure’ in the complex that is Rh.