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Studies on Trypsin Treatment of Red Cells with Special Reference to Differences between Trypsin Preparations
Author(s) -
Heistø H.,
Jensen Leila,
Knuds F.
Publication year - 1971
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1971.tb00568.x
Subject(s) - trypsin , hemolysin , chemistry , antibody , biochemistry , microbiology and biotechnology , biology , enzyme , immunology , virulence , gene
. Red cells were treated with 20 different trypsin preparations. When the red cells were used for detecting Rh‐antibodies, the trypsins gave comparable results provided the solutions had the same trypsin activity as measured by Anson units. When testing for warm haemolysins, the effect on the red cells was dependent on the activity as measured by Anson units of the single trypsin preparation, but there were great differences between trypsin preparations which indicates some kind of qualitative differences between these latter. The findings also suggest that there are differences in specificity between warm haemolysins from different people.