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The Conversion Rate of Human C 3 under Different Storage Conditions
Author(s) -
Teisberg P.
Publication year - 1971
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1971.tb00434.x
Subject(s) - agarose , complement (music) , chemistry , chromatography , biochemistry , complementation , gene , phenotype
. The stability of the third component of human complement (C 3) under different storage conditions has been studied. Conversion of the protein was demonstrated by change in electrophoretic mobility on agarose. C 3 patterns were observed for 4–7 days, 15–24 days and 8–12 months in sera stored at 20, 4 and −23°C, respectively. After storage for 12 months at −75°C there was no sign of C 3 conversion. Addition of merthiolate did not increase C 3 stability. Exposure to air and haemolysate increased C 3 conversion rate.