Premium
Re‐stimulation of Anti‐D in Donors
Author(s) -
Holburn A. M.,
Cleghorn T. E.,
HughesJones N. C.
Publication year - 1970
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1970.tb01508.x
Subject(s) - stimulation , antibody , pregnancy , medicine , andrology , chemistry , endocrinology , immunology , biology , genetics
. 30 D‐negative subjects immunised by pregnancy or transfusion all had anti‐D concentrations of less than 4 μg/ml. Following re‐stimulation with D‐positive cells 14 of the 30 achieved anti‐D concentrations of over 40 μg/ml. The rise in antibody concentration was accompanied by a small rise in the average equilibrium constant.