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Anti‐I T P 1 : An Antibody Showing a Further Association Between the I and P Blood Group Systems
Author(s) -
Booth P. B.
Publication year - 1970
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1970.tb01498.x
Subject(s) - antigenicity , antibody , cord blood , reactivity (psychology) , immunology , antigen , microbiology and biotechnology , medicine , biology , pathology , alternative medicine
. The specificity of an antibody originally thought to be anti‐P 1 has been shown to depend upon the I T antigenicity of P 1 positive cells. Anti‐P 1 agglutinates P 1 + cells irrespective of their I T content, whereas the strength of reaction of anti‐I T P 1 correlates with the I T antigenicity of P 1 + cells having similar P 1 reactivity. Anti‐I T P 1 does not react with adult I T + P 1 — cells, but the original serum weakly agglutinated I T + + P 1 —cells from cord bloods, due to the presence of a trace of free anti‐I T .