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The Recognition of Water‐Soluble I Blood Group Substance 1
Author(s) -
DzierzkowaBorodej Wanda,
Seyfried Halina,
Nichols Margaret,
Reid Marion,
Marsh W. L.
Publication year - 1970
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1970.tb01452.x
Subject(s) - saliva , chemistry , substance p , chromatography , human blood , physiology , biochemistry , medicine , neuropeptide , receptor
. A powerful cold auto anti‐I has been found that is strongly inhibited by hydatid cyst fluid and inhibited to a varying extent by all of the 181 human saliva samples tested. The investigation showed that the inhibition effect was specific for I and that water soluble I blood group substance must be responsible. No correlation could be found between the concentration of I substance in the saliva and the presence of ABH, Lewis or Sda substances. The amount of salivary I substance secreted appears to be a constant feature of the individual. Infants at birth and i adults have high concentrations of I substance in their saliva and the amount of I substance present does not reflect the I status of the red cells.